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Septins

More information in Books or onNLM PubMed
Definition: A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Sept2 protein, rat  0   *Nerve Growth Factors *Septins. Neurosci Res. 2011 May;70(1):85-90.
septin 6 protein, rat  0   *Septins. Mol Cells. 2011 Jul;32(1):89-98.
SEPT12 protein, mouse  EC 3.6.1.-   *Septins. Fertil Steril. 2011 Jan;95(1):363-5
SEPT2 protein, human  EC 3.6.1.-   *Septins.
SEPT1 protein, human  EC 3.1.5.1   *Septins.
sept2 protein, Xenopus  EC 3.6.1.-   *Xenopus Proteins *Septins. Science. 2010 Sep 10;329(5997):1337-40
sept7 protein, Xenopus  EC 3.6.1.-   *Xenopus Proteins *Septins. Science. 2010 Sep 10;329(5997):1337-40
Sept14 protein, mouse  EC 3.6.1.-   *Septins. Mol Biol Cell. 2010 Apr;21(8):1324-34
Sept11 protein, rat  EC 3.1.5.1   *Septins. J Biol Chem. 2009 Jun 19;284(25):17253-65
Sept8 protein, rat  EC 3.6.1.-   *Septins. J Neurochem 2009 Feb;108(4):867-80
SEPT14 protein, human  EC 3.6.1.-   *Septins. Mamm Genome 2007 Nov;18(11):796-807
Sept12 protein, rat  EC 3.6.1.-   *Septins. Cell Motil Cytoskeleton. 2007 Oct;64(10):794-807
Sep1 protein, Drosophila  EC 3.6.1.-   *Drosophila Proteins *Septins. Insect Biochem Mol Biol 2007 May;37(5):430-9
Sept7 protein, mouse  EC 3.6.1.-   *Septins.
Sept7 protein, rat  EC 3.6.1.-   *Septins.
SEPT12 protein, human  EC 3.6.1.-   *Septins. J Pathol 2005 Jul;206(3):269-78
SEPT11 protein, human  EC 3.6.1.-   *Septins. J Biol Chem 2004 Dec 31;279(53):55895-904
SEPT4 protein, human  EC 3.6.1.-   *Septins.
Sept5 protein, rat  EC 3.6.1.-   *Cell Cycle Proteins *Septins.
Sept5 protein, mouse  EC 3.6.1.-   *Septins.
Sept1 protein, mouse  EC 3.1.5.1   *Septins.
Sept6 protein, mouse  EC 3.6.1.-   *Septins.
SEPT10 protein, human  EC 3.6.1.-   *Septins. Biochem Biophys Res Commun 2003 May 2;304(2):393-8
SEPT9 protein, human  EC 3.6.1.-   *Septins. Biochem J 2002 Oct 1;367(Pt 1):2179-87; Proc Natl Acad Sci U S A 1999 May 25;96(11):6428-33
SEPT8 protein, human  EC 3.6.1.-   *Septins. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2002 Jul;34(4):520-5
SEPT6 protein, human  EC 3.6.1.-   *Septins. Genes Chromosomes Cancer 2001 Sep;32(1):82-8
septin 3  EC 3.6.1.-   *Septins. J Biol Chem 2000 Apr 7;275(14):10047-56
Sept9 protein, rat  0   *Septins. FEBS Lett 1999 May 21;451(2):203-8
Sept4 protein, mouse  EC 3.6.1.-   *Septins. Am J Pathol 1998 Nov;153(5):1551-60
SEPT7 protein, human  EC 3.6.1.-   *Cell Cycle Proteins *Septins. Cytogenet Cell Genet 1996;73(3):224-7
SEPT5 protein, human  EC 3.6.1.-   *Cell Cycle Proteins *Septins. Biochem Biophys Res Commun 2000 Jul 5;273(2):723-8; Hum Genet 1997 Nov;101(1):6-12
Sept2 protein, mouse  EC 3.6.1.-   *Septins. Genes Dev 1997 Jun 15;11(12):1535-47

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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