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Receptors, Prostaglandin E, EP2 Subtype

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Definition: A subtype of prostaglandin E receptors that specifically couples to GS ALPHA GTP-BINDING PROTEIN SUBUNITS and subsequently activates ADENYLATE CYCLASE.      Other names Receptor EP2, Prostanoid; EP2, Prostanoid Receptor; Prostanoid Receptor EP2; Prostaglandin E Receptor 2; PGE Receptor, EP2 Subtype
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acid  0   *Azetidines Receptors, Prostaglandin E, EP2 Subtype. Br J Pharmacol. 2011 Dec;164(7):1847-56.
PF 04217329  0   *Acetates *Sulfonamides Receptors, Prostaglandin E, EP2 Subtype/agonists. Exp Eye Res. 2011 Sep;93(3):256-64.
CP 544326  0   *Acetic Acids *Sulfonamides Receptors, Prostaglandin E, EP2 Subtype/agonists. Exp Eye Res. 2011 Sep;93(3):256-64.
Ptger2 protein, rat  0   *Receptors, Prostaglandin E, EP2 Subtype.
Ptger2 protein, mouse  0   *Receptors, Prostaglandin E, EP2 Subtype.
PTGER2 protein, human  0   *Receptors, Prostaglandin E, EP2 Subtype.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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