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Cysteine Loop Ligand-Gated Ion Channel Receptors

More information in Books or onNLM PubMed
Definition: A subfamily of ligand-gated ion channel receptors that share a characteristic loop which is formed by a disulfide bond between two CYSTEINE residues. These receptors typically contain five subunits with the cysteine-loop occurring near an N-terminal extracellular domain.     
Examples Receptors, GABA-A; Receptors, Glycine; Receptors, Nicotinic; Receptors, Serotonin, 5-HT3 		Other names Superfamily, Cys-Loop Receptor; Receptors, Cys-Loop; Receptor Superfamily, Cys-Loop; Cysteine Loop Ligand Gated Ion Channel Receptors; Cys Loop Receptors; Cys Loop Receptor Superfamily; Cys-Loop Receptors; Cys-Loop Receptor Superfamily
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ZACN protein, human  0   *Nerve Tissue Proteins *Cysteine Loop Ligand-Gated Ion Channel Receptors. J Biol Chem 2003 Jan 10;278(2):712-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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