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Phosphatidylinositol 3-Kinase

More information in Books or onNLM PubMed
Definition: A phosphatidylinositol 3-kinase that catalyzes the conversion of 1-phosphatidylinositol into 1-phosphatidylinositol 3-phosphate.  PHOSPHATIDYLINOSITOL 3-KINASES is also available   
Examples Class I Phosphatidylinositol 3-Kinases; Class II Phosphatidylinositol 3-Kinases; Class III Phosphatidylinositol 3-Kinases 		Other names Phosphatidylinositol 3 Kinase; 1 Phosphatidylinositol 3 Kinase; 1-Phosphatidylinositol 3-Kinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HS-104  0   *Imidazoles *Pyridines Phosphatidylinositol 3-Kinase/antagonists & inhibitors. Cancer Lett. 2012 May 1;318(1):68-75
NVP-BKM120  0   *Aminopyridines *Morpholines Phosphatidylinositol 3-Kinase/antagonists & inhibitors. Sci Transl Med. 2010 Sep 29;2(51):51ra70.
8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl-3-trifluoromethylphenyl)-1,3-dihydroimidazo(4,5-c)quinolin-2-one  0   *Imidazoles *Quinolines Phosphatidylinositol 3-Kinase/antagonists & inhibitors. Clin Cancer Res. 2011 Nov 15;17(22):7116-26.
1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one  0   *Pyrimidines *Bicyclo Compounds, Heterocyclic Phosphatidylinositol 3-Kinase/antagonists & inhibitors. J Med Chem. 2011 Nov 10;54(21):7579-87.
SN 30191  0   *Pyrimidinones Phosphatidylinositol 3-Kinase/antagonists & inhibitors. Int J Pharm 2011 Apr 15;408(1-2):138-51
5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one  0   *Flavones Phosphatidylinositol 3-Kinase/antagonists & inhibitors. J Cell Physiol 2011 Jun;226(6):1519-30

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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