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Integrin-Binding Sialoprotein

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Definition: A highly glycosylated and sulfated phosphoprotein that is found almost exclusively in mineralized connective tissues. It is an extracellular matrix protein that binds to hydroxyapatite through polyglutamic acid sequences and mediates cell attachment through an RGD sequence.      Other names Sialoprotein, Integrin-Binding; Sialoprotein, Bone; Sialoprotein 2, Bone; Integrin Binding Sialoprotein; Bone Sialoprotein II; Bone Sialoprotein 2; Bone Sialoprotein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ibsp protein, rat  0   *Integrin-Binding Sialoprotein.
Ibsp protein, mouse  0   *Integrin-Binding Sialoprotein.
IBSP protein, human  0   *Integrin-Binding Sialoprotein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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