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Receptors, Autocrine Motility Factor

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Definition: Cell surface receptors for AUTOCRINE MOTILITY FACTOR, which is the secreted form of GLUCOSE-6-PHOSPHATE ISOMERASE. The receptor has an unusual composition in that it shares some structural similarities with G-PROTEIN-COUPLED RECEPTORS and functions as an ubiquitin protein ligase when internalized.      Other names Receptor, AMF; Tumor Autocrine Motility Factor Receptor; Receptor, Tumor Autocrine Motility Factor; Autocrine Motility Factor Receptor; AMF Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Amfr protein, mouse  EC 6.3.2.-   *Receptors, Autocrine Motility Factor.
AMFR protein, human  EC 6.3.2.19   *Receptors, Autocrine Motility Factor.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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