Definition: A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
Other names T-Cell Co-Stimulator, Inducible; Inducible T Cell Co Stimulator Protein; Inducible T Cell Co Stimulator; ICOS Inducible T Cell Co Stimulator; Co-Stimulator, Inducible T-Cell; CD278 Antigens; Antigen, CD278; Activation Inducible Lymphocyte Immunomediatory Mo; Inducible T-Cell Co-Stimulator; Inducible Costimulator (ICOS); Inducible Co-Stimulator (ICOS); ICOS Inducible T-Cell Co-Stimulator; CD278 Antigen; Antigens, CD278; Activation-Inducible Lymphocyte Immunomediatory Mo