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CTLA-4 Antigen

More information in Books or onNLM PubMed
Definition: An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE.      Other names Cytotoxic T Lymphocyte Associated Antigen 4; Cytotoxic T Lymphocyte Antigen 4; CTLA 4 Antigen; CD152 Antigens; Antigen, CTLA-4; Antigen, CD152; Cytotoxic T-Lymphocyte-Associated Antigen 4; CD152 Antigen; Antigens, CD152; Cytotoxic T-Lymphocyte Antigen 4
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ctla4 protein, rat  0   *CTLA-4 Antigen.
Ctla4 protein, mouse  0   *CTLA-4 Antigen.
CTLA4 protein, human  0   *CTLA-4 Antigen.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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