Definition: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
Other names Receptor, PD1; Receptor, PD-1; PD 1 Receptor; CD279 Antigens; Antigen, CD279; PD1 Receptor; PD-1 Receptor; CD279 Antigen; Antigens, CD279; Programmed Cell Death 1 Protein
