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Polyketides

More information in Books or onNLM PubMed
Definition: Natural compounds containing alternating carbonyl and methylene groups (beta-polyketones), bioenergenetically derived from repeated condensation of acetyl coenzyme A via malonyl coenzyme A, in a process similar to fatty acid synthesis.     
Examples Macrolides 		Other names Ketides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
JBIR-85  0   *Polyketides *Naphthoquinones. J Nat Prod. 2011 Dec 27;74(12):2588-91
colibactin  0   *Peptides *Polyketides Mutagens. Int J Med Microbiol. 2007 Feb;297(1):9-15.
cereoaldomine  0   *Polyketides Leukocyte Elastase/antagonists & inhibitors. J Nat Prod. 2011 Oct 28;74(10):2282-5
trypethelone  0   *Polyketides Leukocyte Elastase/antagonists & inhibitors. J Nat Prod. 2011 Oct 28;74(10):2282-5
cereolactam  0   *Polyketides Leukocyte Elastase/antagonists & inhibitors. J Nat Prod. 2011 Oct 28;74(10):2282-5
botcinic acid  0   *Polyketides Mycotoxins. Mol Plant Pathol. 2011 Aug;12(6):564-79
actinopolysporin C  0   *Polyketides. J Nat Prod. 2011 Sep 23;74(9):1990-5
actinopolysporin B  0   *Polyketides. J Nat Prod. 2011 Sep 23;74(9):1990-5
actinopolysporin A  0   *Polyketides. J Nat Prod. 2011 Sep 23;74(9):1990-5

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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