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grayanotoxin I

under Diterpenes
More information in Books or onNLM PubMed
More on Diterpenes Definition: Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.  GEN; prefer specifics    Other names Norditerpenes; Diterpenes, Labdane; Diterpenes, Cembrane; Labdane Diterpenes; Cembrane Diterpenes; Norditerpenoids; Labdanes; Diterpenoids; Cembranes
SubstanceCAS Registry & nameCategoriesSourceDrugs*
grayanotoxin I [ acetylandromedol,andromedotoxin ]
  RN given refers to (3beta,6beta,14R)-isomer; structure
4720-09-6   *Diterpenes Toxins, Biological
Pharma Action Antihypertensive Agents; Neuromuscular Depolarizing Agents
J Physiol 242(2):471;1974; Am J Physiol 253(3):C136;1978; Arzneim Forsch 28(4):654;1978; Folia Pharmacol Jpn 72:325;1976; J Membrane Biol 31(4):359;1977; J Pharmacol Exp Ther 199(1):247;1976; J Pharmacol Exp Ther 200(2):363;1977; Life Sci 1979;19(5):1651; Toxicon 16:227;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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