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methyl 4-mercaptobutyrimidate

under Imidoesters
More information in Books or onNLM PubMed
More on Imidoesters Definition: Esters of the hypothetical imidic acids. They react with amines or amino acids to form amidines and are therefore used to modify protein structures and as cross-linking agents.  reagents; D25-26 qualif    Other names Imidates
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl 4-mercaptobutyrimidate [ 2-iminothiolane,methyl 4-mercaptobutyrimidate hydrochloride ]
  used as a cross-linking agent to study ribosomal proteins, by making disulfide linkages; RN given refers to parent cpd; structure 		64821-63-2   *Imidoesters
Pharma Action Cross-Linking Reagents 		Biochem Biophys Res Commun 76(2):495;1977; Biochemistry 12(17):3266;1973; Biochemistry 17(25):5399;1978; FEBS Lett 91(1):149;1978; Hoppe Seylers Z Physiol Chem 358(1):137;1977; J Biol Chem 250(24):9434;1975; J Mol Biol 127(3):243;1979; J Mol. Biol 106:995;1976; Methods Enzymol 59:534;1979; Microbios 17:93;1976; Cell 12:417;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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