encyclopedia of medical concepts
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mepitiostane
under Androstanols
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Androstanols
Definition
: Androstanes and androstane derivatives which are substituted in any position with one or more hydroxyl groups.
do not confuse with ANDROSTENOLS
Other names
Hydroxyandrostanes
Substance
CAS Registry & name
Categories
Source
Drugs
*
mepitiostane [ 10364-S,2-alpha,3 alpha-epithio-5 alpha-androstan-17 beta-yl-1-methoxycyclopentyl ether ]
orally active anti-estrogenic steroid; RN refers to (2alpha,3alpha,5alpha,17beta)-isomer; structure
21362-69-6 androstane, 2,3-
epithio-
17-
((1-
methoxycyclopentyl)oxy)-
, (2 alpha,3 alpha,5 alpha,17 beta)
*Androstanols
Pharma Action
Antineoplastic Agents
;
Estrogen Antagonists
;
Anabolic Agents
Gan 68:337;1977; Cancer 41(2):758;1978; Cancer Res 37:4408;1977; Cancer Treat Rep 62(5):743;1978; Folia Endocrinol Jpn 50(2):501;1974; Folia Endocrinol Jpn 50(2):509;1974; Folia Endocrinol Jpn 50(2):511;1974; Gan 69(2):281;1978; Jpn J Pharmacol 24(4):551;1974; Rinsho Ketsueki 20(2):121;1979; Steroids 23(6):929;1974