encyclopedia of medical concepts
ψ
ψ
ψ

aflatoxin B1-2,3-oxide

under Aflatoxin B1
More information in Books or onNLM PubMed
More on Aflatoxin B1 Definition: A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.  /antag permitted but consider also ANTITOXINS; DF: AFB1    Other names Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled; Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled; Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer; Aflatoxin B; NSC-529592; HSDB-3453; Aflatoxin B1, cis(+,-)-Isomer; Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aflatoxin B1-2,3-oxide [ AFB epoxide,AFB1-2,3-oxide,aflatoxin B1-8,9-epoxide ] 42583-46-0 Cyclopent(c)oxireno(4',5')furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,10-dione, 2,3,6a,7a,8a,8b-hexahydro-4-methoxy  Aflatoxin B1/*analogs & derivatives
Pharma Action Carcinogens 		Biochem Biophys Res Comm 60(3):1036;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy