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ψ
dimethyl dithiobispropionimidate
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Imidoesters
Definition
: Esters of the hypothetical imidic acids. They react with amines or amino acids to form amidines and are therefore used to modify protein structures and as cross-linking agents.
reagents; D25-26 qualif
Other names
Imidates
Substance
CAS Registry & name
Categories
Source
Drugs
*
dimethyl dithiobispropionimidate [ dimethyl 3,3'-dithiobis(propionimidate),dimethyl 3,3'-dithiobispropionimidate,dimethyl dithiobispropionimidate dihydrochloride,dimethyl-3,3'-dithiobispropionimidate ]
bifunctional reagent with disulfide group; cross-links membrane proteins & hemoglobin in erythrocytes; RN given refers to parent cpd; structure
59012-54-3
*Imidoesters
Pharma Action
Cross-Linking Reagents
Arch Virol 1979;60(3-4):207; Biochemistry 16(11):2441;1977; Biochemistry 16(12):2629;1977; Biochim Biophys Acta 567(1):247;1979; Cell Shape Surface Architect 17:605;1977; FEBS Lett 1979;104(2):294; FEBS Lett 90(1):123;1978; Isr J Med Sci 11(11):1197;1975; J Biol Chem 249(24);1974; J Biol Chem 250(16):6622;1975; J Biol Chem 252(13):4743;1977; J Biol Chem 253(16):5745;1978; J Immunol 123(2):870;1979; J Virol 1980;33(1):152; Nucleic Acids Res 1979;7(6):1649; Virology 88(2):263;1978