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(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane
under Dioxanes
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Dioxanes
Definition
: 1,4-Diethylene dioxides. Industrial solvents. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), dioxane itself may "reasonably be anticipated to be a carcinogen." (Merck Index, 11th ed)
indust solvents
Substance
CAS Registry & name
Categories
Source
Drugs
*
(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane [ (2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride,WB 4101,WB-4101,WB4101 ]
613-67-2 N-
(2-
(2,6-
dimethoxyphenoxy)ethyl)-
2,3-
dihydro-
1,4-
benzodioxin-
2-
methanamine, hydrochloride
*Dioxanes
Pharma Action
Adrenergic alpha-Antagonists
Brain Res 159(1):125;1978; Eur J Pharmacol 52(3-4):303;1978; J Biol Chem 252(18):6450;1977; J Med Chem 1979;22(9):1125; J Pharm Pharmacol 27(4):295;1975; J Pharm Pharmacol 30(4):259;1978; J Pharm Pharmacol 30(7):444;1978; J Pharm Pharmacol 31(3):188;1979; J Pharm Pharmacol 31(5):337;1979; J Pharmacol Exp Ther 1980;212(3):382; Life Sci 19(1):69;1976; Life Sci 23(4):375;1978; Mol Pharmacol 13:454;1977; Mol Pharmacol 14:403;1978; Naunyn Schmiedebergs Arch Pharmacol1979;307(3):223; Neuropharmacology 16:549;1977
