encyclopedia of medical concepts
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ceforanide
under Cefamandole
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Cefamandole
Definition
: Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate.
Other names
Compound 83405; Cephamandole
Substance
CAS Registry & name
Categories
Source
Drugs
*
ceforanide [ 7-(alpha-(2-aminomethylphenyl)acetamido)-3-((1-carboxymethyltetrazol-5-ylthio)methyl)-3-cephem-4-carboxylic acid,BL-S 786,BL-S786R,cefaronide,ceforanide, monosodium salt ]
RN given refers to (6R-(trans))-isomer
60925-61-3 (6R-
trans)-
7-
(((2-
(aminomethyl)phenyl)acetyl)amino)-
3-
(((1-
(carboxymethyl)-
1H-
tetrazol-
5-
yl)thio)methyl)-
8-
oxo-
5-
thia-
1-
azabicyclo(4.2.0)oct-
2-
ene-
2-
carboxylic acid
Cefamandole/*analogs & derivatives
Pharma Action
Anti-Bacterial Agents
Antimicrob Agents Chemother 10(3):426;1976; Antimicrob Agents Chemother 14(1):1;1978; Antimicrob Agents Chemother 15(2):318;1979; Antimicrob Agents Chemother 16(1):64;1979; Antimicrob Agents Chemother 1979;16(3):386; Antimicrob Agents Chemother 1979;16(5):615; Infection 1979;7(4):176; J Antibiot (Tokyo) 1979;32(7):727; J Antibiot (Tokyo) 29(11):1226;1976; J Antibiot (Tokyo) 30(4):326;1977; J Antibiot (Tokyo) 30(7):576;1977; J Antibiot (Tokyo) 31(4):363;1978
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