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NSC 224131

under Aspartic Acid
More information in Books or onNLM PubMed
More on Aspartic Acid Definition: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.  D-ASPARTIC ACID is also available    Other names (+-)-Aspartic Acid; Mg5Longoral; Mg 5 Longoral; L Aspartic Acid; L Aspartate; Hydrochloride, Aspartate Magnesium; Hydrochloride Aspartic Acid; Hydrobromide Aspartic Acid; Aspartate, Sodium; Aspartate, Potassium; Aspartate, Monosodium; Aspartate, Monopotassium; Aspartate, Magnesium; Aspartate, Disodium; Aspartate, Dipotassium; Aspartate, Calcium; Aspartate, Ammonium; Sodium Aspartate; Potassium Aspartate; Monosodium Aspartate
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NSC 224131 [ N-(phosphonacetyl)-L-aspartate,N-(phosphonoacetyl)-L-aspartate,NSC 224131, disodium salt,NSC 224131, tetrasodium salt,NSC-224131,PALA ]
  inhibitor of aspartate transcarbamylase; bisubstrate ligand; RN refers to (L)-isomer 		51321-79-0 N-(phosphonoacetyl)-L-aspartic acid  Aspartic Acid/*analogs & derivatives Phosphonoacetic Acid/*analogs & derivatives
Pharma Action Antimetabolites, Antineoplastic; Antiviral Agents; Enzyme Inhibitors 		Arch Biochem Biophys 161:76;1974; Biochem Pharmacol 26:81;1977; Biochemistry 17(5):784;1978; Cancer 40(5)Suppl:2640;1977; Cancer Chemother Pharmacol 1979;3(3):135; Cancer Chemother Pharmacol 2(3):183;1979; Cancer Res 1979;39(10):3992; Cancer Res 1980;40(1):86; Cancer Res 36:2720;1976; Cancer Res 37(9):3080;1977; Cancer Res 38(11):3745;1978; Cancer Res 38:371;1978; Cancer Res 39(8):3089;1979; Cancer Trat Rep 1979;63(8):1291; Cancer Treat Rep 1979;63(11-12):1909; Cancer Treat Rep 62(10):1503;1978; Cancer Treat Rep 63(5):775;1979; Cancer Treat Rep 63(6):1095;1979; Cell 9(4):541;1976; Experientia 33(4):428;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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