encyclopedia of medical concepts
ψ
4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol
under Isoxazoles
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Isoxazoles
Definition
: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.
Substance
CAS Registry & name
Categories
Source
Drugs
*
4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol [ LU 2030,LU-2-030,THIP,gaboxadol ]
GABA agonist; inhibitor of GABA uptake systems; structure
64603-91-4
*Isoxazoles
Anesthetics
Appetite Depressants
Pharma Action
Analgesics
;
Anticonvulsants
;
GABA Agonists
Eur J Pharmacol 1979;58(4):485; Life Sci 1979;25(15):1351; Nature 268(6515):53;1977; Nature 280(5720):331;1979; Pharmacol Biochem Behav 1980;12(1):113