Definition: An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Other names Busulphan; Wellcome, Busulfan; Busulfan Wellcome Brand; Busulfan Orphan Brand; Busulfan GlaxoSmithKline Brand; n-Butane-1,3-di(methylsulfonate); Wellcome Brand of Busulfan; Orphan Brand of Busulfan; Myl+¬ran; Myleran; Mylecytan; Myelosan; Glyzophrol; GlaxoSmithKline Brand of Busulfan; Glaxo Wellcome Brand of Busulfan; Busulfex; Busulfan Wellcome
