Definition: A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.
meteneprost [ 9-deoxo-16,16-dimethyl-9-methylene-PGE2,9-deoxo-16,16-dimethyl-9-methyleneprostaglandin E2,9-deoxy-16,16-dimethyl-9-methylene-PGF2,9-methylene-16,16-dimethyl PGE2,9-methylene-PGE2 ] 9-deoxo-9-methylene-PGEs are possible solution to PGE stability problem; stable in aqueous media from pH 1 to 14 & have biological properties similar to corresponding PGEs; cpd tested for use as early