encyclopedia of medical concepts
ψ

pralidoxime

under Pralidoxime Compounds
More information in Books or onNLM PubMed
More on Pralidoxime Compounds Definition: Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.  DF: PRALIDOXIME CPDS    Other names Pyridine Aldoxime Methyl Compounds; 2-PAM Compounds; Compounds, Pralidoxime; Compounds, 2-PAM; 2 PAM Compounds
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pralidoxime [ 2-PAM,1-methylpyridinium-2-aldoxime ion,2-PAM chloride,2-Pam bromide,2-formyl-1-methylpyridinium chloride oxime,2-hydroxyiminomethyl-1-methylpyridinium,2-hydroxyiminomethylpyridinium methylmethanesulfonate,Contrathion,N-methylpyridinium 2-aldoxime methylsulfate,Protopam,Protopam Chloride,SERB brand of pralidoxime mesylate,Wyeth brand of pralidoxime chloride,pralidoxime bromide,pralidoxime chloride,pralidoxime fumarate (1:1),pralidoxime iodide,pralidoxime lactate (1:1),pralidoxime mesylate,pralidoxime methyl sulfate,pralidoxime nitrate (1:1),pralidoxime sulfate (1:1),pralidoxime trichloroacetate,pralidoxime, 14C-labeled,pyridine-2-aldoxime methachloride,pyridine-2-aldoxime methiodide,pyridine-2-aldoxime methochloride ]
  RN given refers to parent cpd; chloride was minor descriptor (75-80); on-line & Index Medicus search PRALIDOXIME COMPOUNDS (66-80) 		6735-59-7   *Pralidoxime Compounds
Pharma Action Antidotes; Cholinesterase Reactivators 		Biochm Pharmacol 27(18):2229;1978; Br J Pharmacol 44(2):368P;1972; J Immunol Methods 1980;35(1-2):157; J Neurosci Res 2:299;1976; Toxicol Appl Pharmacol 40:109;1977 PRALIDOXIME CHLORIDE; PROTOPAM CHLORIDE

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy