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morphiceptin

under Endorphins
More information in Books or onNLM PubMed
More on Endorphins Definition: One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.      Other names Endorphin
SubstanceCAS Registry & nameCategoriesSourceDrugs*
morphiceptin [ NH(4)-Tyr-Pro-Phe-Pro-CONH(2),Tyr-Pro-Phe-D-Pro-NH2,Tyr-Pro-Phe-Pro amide,beta-casomorphine(1-4) amide,deproceptin,morphiceptin monohydrochloride, (L-Tyr-L-Pro-L-Phe-L-Pro)-isomer,morphiceptin, (L-Tyr-D-Pro-L-Phe-L-Pro)-isomer,morphiceptin, (L-Tyr-L-Pro-L-Phe-D-Pro)-isomer,tyrosyl-prolyl-phenylalanyl-D-prolinamide ]
  synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors; is the amide of a fragment of the milk protein beta casein; deproceptin i
74135-04-9   *Endorphins
Pharma Action Analgesics; Convulsants
Science 1981;212(4490):75

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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