Definition: Abnormal immunoglobulins, especially IGG or IGM, that precipitate spontaneously when SERUM is cooled below 37 degrees Celsius. It is characteristic of CRYOGLOBULINEMIA.
cold agglutinins [ anti-pr cold agglutinin,cold agglutinin Li,cold agglutinin Om,cold agglutinin Vo,cold agglutinin, anti-pr,cryoagglutinins ] antibodies that agglutinate bacteria or erythrocytes more efficiently at temperatures below 37C than at 37C; autoantibodies causing hemolytic anemia in patients with cold agglutinin disease
