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methylazoxymethanol
under Methylazoxymethanol Acetate
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Methylazoxymethanol Acetate
Definition
: The aglycone of CYCASIN. It acts as a potent carcinogen and neurotoxin and inhibits hepatic DNA, RNA, and protein synthesis.
Other names
Acetate, Methylazoxymethanol; (Methyl-
ONN-
azoxy)methanol Acetate
Substance
CAS Registry & name
Categories
Source
Drugs
*
methylazoxymethanol [ methazoxymethanol ]
a neuroteratogen; reacts with guanine residues of DNA & RNA forming 7-methylguanine adduct products; carcinogenicity probably related to biological decomposition into methyldiazonium ion, the ultimate
590-96-5
Methylazoxymethanol Acetate/*analogs & derivatives
Mitosis/drug effects
Pharma Action
Alkylating Agents
;
Carcinogens
;
Teratogens
Cancer Biochem Biophys 1981;5(2):119