Definition: Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.
ovomacroglobulin [ hen egg white ovomacroglobulin,ovostatin ] macroglobulin from freshly laid egg white with protease inhib activity toward trypsin, papain, & thermolysin; contains 4 subunits of equal MW(175,000); subunit & amino acid comp related to human serum