Definition: Compounds with three fused rings that appear like a naphthalene fused to piperidone or like a benz(de)isoquinoline-1,3-dione (not to be confused with BENZYLISOQUINOLINES which have a methyl separating the naphthyl from the benzyl rings). Members are CYTOTOXINS.
amonafide [ FA 142,5-amino-2-(2-dimethylaminoethyl)benzo(de)isoquinolin-1,3-dione,M-FA 142,M-FA-142,MFA 142,MFA-142,NSC 308847,NSC-308847,benzisoquinolinedione,nafidimide ] DNA topoisomerase II inhibitor;structure given in first source