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cilastatin, imipenem drug combination

under Imipenem
More information in Books or onNLM PubMed
More on Imipenem Definition: Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.      Other names N-Formimidoylthienamycin; Imipemide; N Formimidoylthienamycin; MK 0787; Anhydrous Imipenem; MK0787; MK-0787; Imipenem, Anhydrous
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cilastatin, imipenem drug combination [ MK 0787-MK 0791 mixture,MK 787-MK 791 mixture,Merck Frosst brand of imipenem-cilastatin, sodium salt,Merck Sharp & Dohme brand of imipenem-cilastatin, sodium salt,Merck brand of imipenem-cilastatin, sodium salt,Primaxin,Thienam,Tienam 500,Zienam,imipenem - cilastatin,imipenem-cilastatin,imipenem-cilastatin, sodium salt ]
  combination of imipenem and cilastatin
92309-29-0   *Imipenem *Cilastatin Drug Combinations J Antimicrob Chemother 1985;15(2):233 PRIMAXIN; IMIPENEM AND CILASTATIN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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