encyclopedia of medical concepts
ψ
ψ
ψ

acetorphan

under Thiorphan
More information in Books or onNLM PubMed
More on Thiorphan Definition: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.      Other names Thiorphan, (S)-Isomer; Thiorphan, (R)-Isomer; (3-Mercapto-2-benzylpropionyl)glycine; Tiorphan
SubstanceCAS Registry & nameCategoriesSourceDrugs*
acetorphan [ N-(3-acetylmercapto-2-benzylpropanoyl)glycine benzyl ester,acetorphan, (R)-isomer,acetorphan, (S)-isomer,ecadotril,racecadotril,retorphan,sinorphan ]
  parenterally active enkephalinase inhibitor 		81110-73-8 Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, (+-)  Thiorphan/*analogs & derivatives Neprilysin/antagonists & inhibitors
Pharma Action Antidiarrheals; Protease Inhibitors 		J Pharmacol Exp Ther 1986;237(3):937

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy