encyclopedia of medical concepts
ψ
onapristone
under Gonanes
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Gonanes
Definition
: Steroids containing the fundamental tetracyclic unit with no methyl groups at C-10 and C-13 and with no side chain at C-17. The concept includes both saturated and unsaturated derivatives.
includes gonenes, gonadienes, gonatrienes
Substance
CAS Registry & name
Categories
Source
Drugs
*
onapristone [ 11 beta-(4-dimethylaminophenyl)-17 alpha-hydroxy-17 beta-(3-hydroxypropyl)-13 alpha-methyl-4,9-gonadien-3-one,ZK 299,ZK 98.299,ZK 98299,ZK-299,ZK-98299 ]
induces vaginal bleeding and luteal regression in monkeys; structure given in first source; progesterone antagonist
96346-61-1 Estra-
4,9-
dien-
3-
one, 11-
(4-
(dimethylamino)phenyl)-
17-
hydroxy-
17-
(3-
hydroxypropyl)-
, (11beta,13alpha,17alpha)
*Gonanes
Pharma Action
Antineoplastic Agents
;
Fertility Agents, Female
;
Hormone Antagonists
Contraception 1987;35(4):409