Definition: A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS.
atrial natriuretic factor prohormone (1-98) [ ANF (1-98),ANF (Asn1-Arg98),ANP (1-98),atrial natriuretic factor (1-98),atrial natriuretic factor precursor (1-98),atriopeptin (1-98),pro-ANF (1-98),pro-ANF(1-98) ] the 98-amino acid fragment at the N-terminal of the ANP prohormone, ATRIAL NATRIURETIC FACTOR (1-126); its circulating level is related to heart diseases.