Definition: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders.
Other names Tetrahydroaminoacridine; Woods Brand of Tacrine Hydrochloride; Tenakrin; Tacrine Hydrochloride; Romotal; Parke Davis Brand of Tacrine Hydrochloride; OTL Pharm Brand of Tacrine Hydrochloride; Horizon Brand of Tacrine Hydrochloride; Cognex; 9-Amino-1,2,3,4-Tetrahydroacridine; 1,2,3,4-Tetrahydroaminoacridine; 1,2,3,4-Tetrahydro-9-acridinamine; THA
velnacrine [ 1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate,1,2,3,4-tetrahydro-9-aminoacridine-1-ol,1-hydroxytacrine,9-ATHCO,9-amino-1,2,3,4-tetrahydroacridin-1-ol,HP 029,HP-029,velnacrine maleate ] RN given refers to (+-)-isomer; RN for cpd without isomeric designation not available 8/88; structure in first source; potential Alzheimer's disease drug but trial halted due to abnormal liver tests
