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conantokin-T

under Mollusk Venoms
More information in Books or onNLM PubMed
More on Mollusk Venoms Definition: Venoms from mollusks, including CONUS and OCTOPUS species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerupin, maculotoxin, surugatoxin, conotoxins, and murexine.  /antag permitted but consider also ANTIVENINS; /enzymol permitted; coordinate IM with specific mollusk (IM or NIM)    Other names Snail Venoms; Octopus Venoms; Conus Venoms; Venoms, Snail; Venoms, Octopus; Venoms, Mollusk; Venoms, Mollusc; Venoms, Conus; Venom, Snail; Venom, Octopus; Venom, Mollusk; Venom, Conus; Snail Venom; Octopus Venom; Mollusk Venom; Mollusc Venoms; Conus Venom
SubstanceCAS Registry & nameCategoriesSourceDrugs*
conantokin-T
  from cone snail Conus tulipa; a 21-amino acid peptide which induces sleep-like symptoms in young mice; has N-methyl-D-aspartate antagonist activity; amino acid sequence given in first source
127476-26-0   *Mollusk Venoms *Peptides
Pharma Action Excitatory Amino Acid Antagonists
J Biol Chem 1990;265(11):6025

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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