Definition: Regulatory proteins and peptides that are signaling molecules involved in the process of PARACRINE COMMUNICATION. They are generally considered factors that are expressed by one cell and are responded to by receptors on another nearby cell. They are distinguished from HORMONES in that their actions are local rather than distal.
general or unspecified; prefer specifics; coordinate with PARACRINE COMMUNICATION if pertinent; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS is also available
Other names Peptide Factors, Paracrine; Paracrine Protein Factors; Paracrine Peptide Factors; Growth Factors
myotrophin [ Increlex,MTPN protein, human,Mtpn protein, mouse,Mtpn protein, rat,granule cell differentiation protein,mecasermin,myotrophin protein, human,myotrophin protein, mouse,myotrophin protein, rat ] a 12 kDa protein consists of 117 amino acids; may play a role in the differentiation of cerebellar neurons, particularly the granule cells; associated with cardiac hypertrophy; RefSeq NM_024374 (rat);
