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saruplase

under Urokinase-Type Plasminogen Activator
More information in Books or onNLM PubMed
More on Urokinase-Type Plasminogen Activator Definition: A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.      Other names Urokinase; Urinary Plasminogen Activator; U-Plasminogen Activator; Plasminogen Activator, Urokinase-Type; Urokinase Type Plasminogen Activator; U Plasminogen Activator; Single Chain Urokinase Type Plasminogen Activator; Single-Chain Urokinase-Type Plasminogen Activator; Renokinase; Kidney Plasminogen Activator; Abbokinase; U-PA Drugs: KINLYTIC
SubstanceCAS Registry & nameCategoriesSourceDrugs*
saruplase [ A-74187,Rescupase,pro-urokinase,prourokinase (enzyme-activating),recombinant unglycosylated single-chain urokinase-type plasminogen activator ] 99149-95-8   *Urokinase-Type Plasminogen Activator Recombinant Proteins Enzyme Precursors
Pharma Action Fibrinolytic Agents
Arzneimittelforschung 1990;40(10):1180

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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