encyclopedia of medical concepts
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salivary plasminogen activator alpha 1, Desmodus rotundus
under Plasminogen Activators
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Plasminogen Activators
Definition
: A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.
/antag: consider also PLASMINOGEN INACTIVATORS
Other names
Uterine Tissue Plasminogen Activator; Uterine-
Tissue Plasminogen Activator; Plasminogen Activator; Extrinsic Plasminogen Activators
Substance
CAS Registry & name
Categories
Source
Drugs
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salivary plasminogen activator alpha 1, Desmodus rotundus [ DSPA alpha 1 protein, Desmodus rotundus,Desmodus salivary plasminogen activator,desmoteplase,salivary plasminogen activator, vampire bat ]
displays strict fibrin specificity; cleared fourfold slower from circulation than t-PA
0
*Plasminogen Activators
Recombinant Proteins
Pharma Action
Fibrinolytic Agents
Circulation 1991;84(1):244