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colforsin

under Forskolin
More information in Books or onNLM PubMed
More on Forskolin Definition: Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive ionotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.      Other names Coleonol
SubstanceCAS Registry & nameCategoriesSourceDrugs*
colforsin [ 6-(3-dimethylaminopropionyl)forskolin,N,N-dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl ester HCl,NKH 477,NKH-477,NKH477 ]
  acts as direct activator of adenyl cyclase; improves drug-induced cardiac failure 		138605-00-2 beta-Alanine, N,N-dimethyl-, 5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl ester, hydrochloride, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))  Forskolin/*analogs & derivatives
Pharma Action Adjuvants, Immunologic; Bronchodilator Agents; Cardiotonic Agents; Vasodilator Agents 		Circ Res 1992 Jul;71(1):70-81

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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