encyclopedia of medical concepts
ψ

simendan

under Hydrazones
More information in Books or onNLM PubMed
More on Hydrazones Definition: Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)  do not confuse with HYDRAZINES   
SubstanceCAS Registry & nameCategoriesSourceDrugs*
simendan [ ((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile,Abbott brand of Levosimendan,Levosimendan,OR 1259,OR-1259,OR-1855,Simadax,dextrosimendan ]
  neuroprotectant; a troponin modifier, a phosphodiesterase III inhibitor, and an inhibitor of voltage-sensitive Ca(2+) current; structure given in second source
131741-08-7   *Hydrazones *Pyridazines
Pharma Action Anti-Arrhythmia Agents; Cardiotonic Agents; Phosphodiesterase Inhibitors; Vasodilator Agents
Adv Exp Med Biol 1992;311:423; Pharmacol Toxicol 1994 Apr-May;74(4-5):244-8

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify.
We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy