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anidulafungin

under Echinocandins
More information in Books or onNLM PubMed
More on Echinocandins Definition: Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.      Other names Pneumocandins; Mulundocandins; Aculeacins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
anidulafungin [ Eraxis,LY 303366,LY-303366,LY303366 ]
  a cyclic hexapeptide echinocandin; antifungal by noncompetitively inhibiting 1,3-beta-D-glucan synthase 		0   *Echinocandins
Pharma Action Antifungal Agents 		Antimicrob Agents Chemother 1996 Aug;40(8):1811-6 ERAXIS

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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