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lenalidomide

under Thalidomide
More information in Books or onNLM PubMed
More on Thalidomide Definition: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppresive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.      Other names Thalomid; Sedoval; Celgene Brand of Thalidomide Drugs: THALOMID
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lenalidomide [ 2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H- isoindol-2-yl)-,3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione,CC 5013,CC-5013,CC5013,Celgene brand of lenalidomide,IMiD3 cpd,Revimid,Revlimid ]
  an immunomodulator 		191732-72-6   Thalidomide/*analogs & derivatives
Pharma Action Antineoplastic Agents 		Clin Exp Immunol 2002 Oct;130(1):75-84 REVLIMID

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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