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aflibercept

under Recombinant Fusion Proteins
More information in Books or onNLM PubMed
More on Recombinant Fusion Proteins Definition: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.  do not confuse with MEMBRANE FUSION PROTEINS; VIRAL FUSION PROTEINS; MUTANT CHIMERIC PROTEINS; or ONCOGENE PROTEINS, FUSION    Other names Fusion Proteins, Recombinant; Proteins, Recombinant Hybrid; Proteins, Recombinant Fusion; Proteins, Recombinant Chimeric; Recombinant Hybrid Proteins; Recombinant Chimeric Proteins; Hybrid Proteins, Recombinant; Chimeric Proteins, Recombinant
SubstanceCAS Registry & nameCategoriesSourceDrugs*
aflibercept [ eylea,AVE 0005,AVE 005,AVE-0005,AVE-005,AVE0005,AVE005,VEGF Trap - regeneron,VEGF Trap-Eye,VEGF-Trap ]
  consists of the second and third Ig domains of VEGFR1 and VEGFR2, respectively, fusion to the Fc region of IgG1; putative antineoplastic agent that binds all VEGF-A isoforms; possible medicine for eye 		0   *Recombinant Fusion Proteins Drugs R D 2008;9(4):261-9 EYLEA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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