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Blood-Testis Barrier

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Definition: A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.  coord IM with endogenous substance /metab (IM) or exogenous substance /pharmacokin (IM)   
See Also Capillary Permeability 		Other names Testis-Blood Barrier; Testis-Blood Barriers; Testis Blood Barrier; Blood-Testis Barriers; Blood Testis Barrier; Barriers, Testis-Blood; Barriers, Blood-Testis; Barrier, Testis-Blood; Barrier, Blood-Testis

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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