Hepatic Encephalopathy (definition)

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Hepatic Encephalopathy

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Definition: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Other names Portosystemic Encephalopathy; Encephalopathy, Hepatic; Stupors, Hepatic; Stupor, Hepatic; Portosystemic Encephalopathies; Portal-Systemic Encephalopathies; Portal Systemic Encephalopathy; Hepatocerebral Encephalopathies; Hepatic Stupors; Hepatic Encephalopathies; Hepatic Comas; Encephalopathy, Portal Systemic; Encephalopathies, Portosystemic; Encephalopathies, Portal-Systemic; Encephalopathies, Hepatocerebral; Encephalopathies, Hepatic; Comas, Hepatic; Coma, Hepatic; Portal-Systemic Encephalopathy; Hepatocerebral Encephalopathy

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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