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Immune Complex Diseases

More information in Books or onNLM PubMed
Definition: Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.  dis caused by deposition of antigen-antibody complexes with resultant damage to tissue; "immune complex"   
Examples Arthus Reaction; Purpura, Schoenlein-Henoch; Serum Sickness; Vasculitis, Leukocytoclastic, Cutaneous 		Other names Type III Hypersensitivity; Hypersensitivity, Type III; Type III Hypersensitivities; Immune Complex Disease; Hypersensitivities, Type III; Diseases, Immune Complex; Disease, Immune Complex

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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