Definition: Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
Other names Type III Hypersensitivity; Hypersensitivity, Type III; Type III Hypersensitivities; Immune Complex Disease; Hypersensitivities, Type III; Diseases, Immune Complex; Disease, Immune Complex