Job's Syndrome (definition)

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ψ ψ	Job's Syndrome

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Definition: Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.

Other names Hyperimmunoglobulin E-Recurrent Infection Syndrome; Hyper-Immunoglobulin E Syndrome, Autosomal Recessi; Hyper-IgE Syndrome, Autosomal Recessive; HIES, Autosomal Recessive; Syndromes, Hyperimmunoglobulinemia E; Syndrome, Job's; Syndrome, Hyperimmunoglobulinemia E; Syndrome, Hyper-IgE; Jobs Syndrome; Job Syndrome; Hyperimmunoglobulinemia E Syndromes; Hyperimmunoglobulin E Recurrent Infection Syndrome; Hyper-IgE Syndromes; Hyper Immunoglobulin E Syndrome, Autosomal Recessi; Hyper Immunoglobulin E Syndrome, Autosomal Dominan; Hyper IgE Syndrome, Autosomal Recessive; Hyper IgE Syndrome, Autosomal Dominant; Hyper IgE Syndrome; HIESs, Autosomal Recessive; HIESs, Autosomal Dominant

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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