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Mink Cell Focus-Inducing Viruses

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Definition: Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.  infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) + TUMOR VIRUS INFECTIONS (IM); add also LEUKEMIA, EXPERIMENTAL (IM), or LEUKEMIA (IM) (for spontaneous leukemia), or ERYTHROLEUKEMIA (IM) if pertinent    Other names MCF Viruses; Viruses, MCF; Virus, MCF; Mink cell focus inducing virus; Mink Cell Focus Inducing Viruses; MCF Virus; Mink cell focus-inducing virus

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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