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Parkinson Disease, Postencephalitic

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Definition: Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754)  DF: PARKINSON DIS POSTENCEPH    Other names Postencephalitic Parkinsonism; Parkinsonism, Viral Meningoencephalitic; Encephalitis Lethargica Type Parkinsonism; Postencephalitis Parkinsonian Syndrome; Postencephalitic Economo Type Parkinsonism; Post Encephalitic Parkinson Disease; Parkinsonisms, Viral Meningoencephalitic; Parkinsonism, Postencephalitic Economo-Type; Parkinson Disease, Post Encephalitic; Meningoencephalitic Parkinsonism, Viral; Economo-Type Parkinsonism, Postencephalitic; von Economo Encephalitis Type Parkinsonism; Viral Meningoencephalitic Parkinsonism; Postencephalitic Parkinson Disease; Postencephalitic Economo-Type Parkinsonism; Post-Encephalitic Parkinson Disease; Parkinsonism, Postencephalitic; Parkinsonian Syndrome, Postencephalitis; Parkinson Disease, Post-Encephalitic

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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