Definition: A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.
IM GEN only; coord NIM with specific disease or other concept (IM);
Other names Rietveld Refinement; Refinement, Rietveld; Least-Squares Analyses; Least Squares Analysis; Analysis, Least Squares; Analyses, Least-Squares; Least Squares; Analysis, Least-Squares