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Genes, abl

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Definition: Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.  abl stands for "ABelson Leukemia"   
See Also Fusion Proteins, bcr-abl; Oncogene Proteins v-abl; Proto-Oncogene Proteins c-abl 		Other names v-abl Genes; c-abl Genes; abl Genes; v-abl Oncogene; v-abl Gene; v abl Oncogenes; v abl Genes; c-abl Proto-Oncogene; c-abl Gene; c abl Proto Oncogenes; bcr-v-abl Oncogene; bcr-abl Proto-Oncogene; c abl Genes; bcr v abl Oncogenes; bcr abl Proto Oncogenes; abl Oncogenes; abl Gene; Proto-Oncogenes, c-abl; Proto-Oncogenes, bcr-abl; Proto-Oncogene, c-abl

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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