Bone Marrow Purging (definition)

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ψ	Bone Marrow Purging

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Definition: Techniques for the removal of subpopulations of cells (usually residual tumor cells) from the bone marrow ex vivo before it is infused. The purging is achieved by a variety of agents including pharmacologic agents, biophysical agents (laser photoirradiation or radioisotopes) and immunologic agents. Bone marrow purging is used in both autologous and allogeneic BONE MARROW TRANSPLANTATION.

coord IM with purging agent or method (IM with no qualif)
See Also Bone Marrow Transplantation; Hematopoietic Stem Cell Transplantation; Immunomagnetic Separation

Other names Hematopoietic Stem Cell Purging; Purging, Bone Marrow

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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